Monday, October 25, 2004

 

DNA: a complex volume

From The Speculist

Ten years ago most genetic scientists thought that the human genome consisted of 100,000 or more genes.
[...]
After further analysis, scientists in the U.S., Asia, and Europe announced this week that the estimate of functioning human genes is only 20,000 to 25,000.
[...]
This is good news. If finding the cause of a genetic disease were like finding a needle in a haystack, the size of the haystack is only 25% of the size we thought it was a decade ago.
I hope the Speculist is right, but have my doubts that this will simplify things quite as much as hoped.

If creating a human only takes one-fourth as many genes as previously thought, then the interrelationships between those genes (and/or the physical characteristics they inspire) must be correspondingly more complex.

Many genes will have one-to-one relationships to specific undesirable conditions, but many others will depend on increasingly complex interactions. To be honest, I would have preferred more genes and simpler relationships; volume scales better than complexity.